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Manufacture of basic pharmaceutical products and pharmaceutical preparations

Current registrations 146division 21: 375
Starters, 12 months 53.4 per 100 · Belgium 8.9
Bankruptcies, 12 months 16.8 per 1,000 registrations · Belgium 6.2
Employment (FTE) 3,54638 employers · latest accounts
Median age 10.6 yearsBelgium 8.1 years
E-invoicing via Peppol 90.4%132 of 146 companies in the Peppol Directory · Belgium 85.0%

Filed accounts

NACE 21100 · financial year 2025 · 109 filed annual accounts
Median solvency
39.2%
division 44.2% · Belgium 46.1%
Median net result
€8,208
division €23,782 · Belgium €16,500
Median equity
€210,214
division €450,490 · Belgium €98,350
Loss-making
44.0%
division 40.0% · Belgium 26.7%
Negative equity
27.5%
division 18.3% · Belgium 12.4%
Median return on equity
9.7%
division 9.5% · Belgium 15.9%
Median liquidity
1.85
division 1.62 · Belgium 1.66
Filed late
36.9%
financial year 2024, 111 filings · division 32.2% · Belgium 38.4%
Missing or 90 days late
3.4%
of 119 companies with annual accounts · division 3.3% · Belgium 5.4%
Per financial year202020212022202320242025
Median solvency 32.1%37.6%36.9%37.9%40.8%39.2%
Median net result €12,702€14,742€6,934€10,515€8,621€8,208

Hold your customer's or competitor's figures against them in the Sector benchmark

Bankruptcies

Bankruptcies, 5 years, still registered
2
1.37% of the registrations · Belgium 1.68%
Running bankruptcies
2
13.7 per 1,000 registrations

Recent bankruptcies

Date Company
10-03-2026 Amalus Therapeutics
BE 0803.929.268
27-10-2025 UNIZIMA
BE 0744.643.759

Every bankruptcy in division 21, last 90 days

Spread across the country

by region and province · 137 of 146 enterprises with a registered office on file · a sole trader has no published seat
  • Flanders 66 · 48.2%
  • Wallonia 52 · 38.0%
  • Brussels 13 · 9.5%
  • Abroad 6 · 4.4%
fewer moremax 20

Largest employers

NACE 21100 as first main activity · staff from the latest accounts
  1. 1 BAXALTA BELGIUM MANUFACTURINGLessines 1,197 FTEfinancial year 2026
  2. 2 AJINOMOTO OMNICHEMWetteren 863 FTEfinancial year 2026
  3. 3 PolyPeptideBraine-l'Alleud 485 FTEfinancial year 2025
  4. 4 Prothya Biosolutions BelgiumBrussels 349 FTEfinancial year 2026
  5. 5 Catalent GosseliesCharleroi 147 FTEfinancial year 2025

Joint committees

from the latest accounts of 46 companies
  • 207 White-collar workers in the chemical industry 32
  • 116 Chemical industry 18
  • 200 Auxiliary committee for white-collar workers 8
  • 313 Pharmacies and pricing offices 2
  • 209 White-collar workers in metal manufacturing 1
  • 302 Hotels and catering 1
  • 330 Health institutions and services 1

Source: the annual accounts at the National Bank. One filing can name more than one committee.

Division 21: Pharmaceuticals

Related activities

2 other activities
Activity Registrations Starters, 12 months Bankruptcies, 12 months FTE
Manufacture of basic pharmaceutical products and pharmaceutical preparations21201 149 4 1 25,630
Manufacture of basic pharmaceutical products and pharmaceutical preparations21209 97 2 0 1,617

Bankruptcies per year in division 21

Per year20152016201720182019202020212022202420252026
Bankruptcies11111113231
Jobs lost1911111814110924

2026 through April. Every bankruptcy, also of companies that have since left the register. Source: Statbel (Directorate-General Statistics), NACE classification of 2008.

Staff cost per FTE in NACE division 21

104 employers
Median
€94,200
Belgium €61,400
Middle half
€69,400 to €114,100
half of the employers lie between
Place among sectors
2 of 78
sectors with a median staff cost per FTE, highest first
By size class
SizeMedianMiddle halfEmployers
fewer than 10 FTE €71,000 €53,500 to €110,200 40
10 to 49 FTE €102,100 €95,100 to €128,700 28
50 to 249 FTE €82,700 €74,400 to €95,300 21

Foreign control in NACE division 21

309 registered companies

Subsidies in this sector

per register · legal entities with an enterprise number
  • Flemish subsidies €65.0m awarded 71 recipients · 2022 to 2025 · largest: Onderzoeksproject
  • Federal transfers 1.2m amount as published 2 recipients · 2023 to 2025 · largest: Subsidies voor de verbetering van telecommunicatieconnectiviteit
  • EU budget €15.6m attributed share 10 recipients · 2021 to 2025 · largest: Horizon Europe
  • EU research €38.2m EU contribution 15 recipients · 2008 to 2026 · largest: Horizon 2020

Explore every recipient in this sector

Insights on Manufacture of basic pharmaceutical products and pharmaceutical preparations

Balance sheet and result. 27.5% of the annual accounts show negative equity, against 12.4% in Belgium. 44.0% of the annual accounts close with a loss, against 26.7% in Belgium. The median net result of €8,208 is below Belgium's €16,500.

Bankruptcies. The median bankruptcy probability of 0.4% is above Belgium's 0.2%.

Inflow and structure. 6.2% of the companies are sole traders, against 41.6% in Belgium. Wallonia holds 39.7% of the seats, against 22.7% in Belgium. In 12 months, 3.4 of 100 companies started, against 8.9 in Belgium. That is fewer than in 83% of the 87 NACE divisions.

Staff and filing. The 5 largest employers hold 3,041 of the 3,546 FTE: 85.8%.

Direction. Median solvency rose from 32.1% in financial year 2020 to 39.2% in financial year 2025. The median net result fell from €12,702 in financial year 2020 to €8,208 in financial year 2025.

The comparison with Belgium as a whole and with the other divisions is as of 08-11-2026 05:30.

Method and sources

Every company registered today counts under its main activities in the KBO. Establishment units do not count. Staff counts once, under the employer's first main activity, from its latest accounts and only where it fits the staff costs. The count follows the NACE 2025 classification, the version in which code 21100 exists.

The bankruptcies over five years count only companies still registered today, because the activity of a company that left the register is not kept. So they are fewer than the bankruptcies of those years, and the figure is not a probability for the future. Over twelve months the count is nearly complete, because a bankrupt company stays registered while its bankruptcy runs. A company with more than one main activity counts in each of those sectors.

The comparison with Belgium as a whole and with the other NACE divisions rests on an overview of every division, counted again each night. Each division is counted in the version of the NACE classification in which it exists. A standing such as "more than in 80%" compares with the other divisions that have the figure. A division's bankruptcy probability is the median over its companies with a score. Belgium here counts the 1,276,474 companies with a main activity, because only those belong to a division. The other 699,509 registrations publish no activity.

Each median is the value of the middle company, computed over the annual accounts of financial year 2025, and is shown only from 30 accounts. A share (loss-making, negative equity) counts that year's accounts with that trait. Accounts are late when they are filed after the statutory deadline. The direction per financial year follows the companies still registered today. Missing or 90 days late counts the companies with accounts missing today, or whose latest were filed more than 90 days after the deadline. The dossier follows the same rule.