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Manufacture of basic pharmaceutical products and pharmaceutical preparations

NACE 21
Current registrations 375
Starters, 12 months 112.9 per 100 · Belgium 8.9
Bankruptcies, 12 months 25.3 per 1,000 registrations · Belgium 6.2
Employment (FTE) 30,792123 employers · latest accounts
Median age 12.5 yearsBelgium 8.1 years
E-invoicing via Peppol 88.0%330 of 375 companies in the Peppol Directory · Belgium 85.0%

Activities

NACE division 21 · 3 activities

Filed accounts

NACE division 21 · financial year 2025 · 279 filed annual accounts
Median solvency
44.3%
Belgium 46.1%
Median net result
€23,776
Belgium €16,516
Median equity
€444,407
Belgium €98,395
Loss-making
40.1%
Belgium 26.7%
Negative equity
18.3%
Belgium 12.4%
Median return on equity
9.3%
Belgium 15.9%
Median liquidity
1.62
Belgium 1.66
Filed late
32.2%
financial year 2024, 236 filings · Belgium 38.4%
Missing or 90 days late
3.3%
of 306 companies with annual accounts · Belgium 5.4%
Per financial year20182019202020212022202320242025
Median solvency --34.8%38.6%40.1%40.4%44.0%44.9%
Median net result --€20,327€20,024€18,463€18,865€22,662€23,776
Filed late 36.0%47.8%35.2%36.0%33.8%34.1%32.2%-

Hold your customer's or competitor's figures against them in the Sector benchmark

Staff cost per FTE in NACE division 21

104 employers
Median
€94,200
Belgium €61,400
Middle half
€69,400 to €114,100
half of the employers lie between
Place among sectors
2 of 78
sectors with a median staff cost per FTE, highest first
By size class
SizeMedianMiddle halfEmployers
fewer than 10 FTE €71,000 €53,500 to €110,200 40
10 to 49 FTE €102,100 €95,100 to €128,700 28
50 to 249 FTE €82,700 €74,400 to €95,300 21

Bankruptcies

Bankruptcies, 5 years, still registered
12
3.20% of the registrations · Belgium 1.68%

Bankruptcies per year in division 21

Per year20152016201720182019202020212022202420252026
Bankruptcies11111113231
Jobs lost1911111814110924

2026 through April. Every bankruptcy, also of companies that have since left the register. Source: Statbel (Directorate-General Statistics), NACE classification of 2008.

Recent bankruptcies

Date Company
24-04-2026 San'Up
BE 0693.818.729
10-03-2026 Amalus Therapeutics
BE 0803.929.268
27-10-2025 UNIZIMA
BE 0744.643.759
27-10-2025 Quantoom Biosciences
BE 0744.643.858
10-10-2025 UNIVERCELLS
BE 0502.742.288
02-09-2025 EXOTHERA
BE 0744.643.660
15-04-2025 ROMARK BELGIUM
BE 0536.645.867
24-01-2025 ORGENESIS SERVICES SRL
BE 0790.353.624

Every bankruptcy in division 21, last 90 days

Spread across the country

by region and province · 358 of 375 enterprises with a registered office on file · a sole trader has no published seat
  • Flanders 169 · 47.2%
  • Wallonia 131 · 36.6%
  • Brussels 39 · 10.9%
  • Abroad 19 · 5.3%
fewer moremax 60

Largest employers

NACE division 21 · staff from the latest accounts
  1. 1 GlaxoSmithKline BiologicalsRixensart 8,371 FTEfinancial year 2025
  2. 2 Janssen PharmaceuticaBeerse 5,325 FTEfinancial year 2025
  3. 3 PFIZER MANUFACTURING BELGIUMPuurs-Sint-Amands 4,021 FTEfinancial year 2025
  4. 4 BAXALTA BELGIUM MANUFACTURINGLessines 1,197 FTEfinancial year 2026
  5. 5 Organon HeistHeist-op-den-Berg 1,005 FTEfinancial year 2025

Joint committees

from the latest accounts of 150 companies
  • 207 White-collar workers in the chemical industry 112
  • 116 Chemical industry 60
  • 200 Auxiliary committee for white-collar workers 20
  • 313 Pharmacies and pricing offices 5
  • 209 White-collar workers in metal manufacturing 2
  • 321 Wholesale distributors of medicines 2
  • 100 Auxiliary committee for blue-collar workers 1
  • 111 Metal, mechanical and electrical engineering 1
Show the 11 others
  • 119 Food trade 1
  • 120 Textile industry 1
  • 136 Paper and cardboard processing 1
  • 145 Horticulture 1
  • 201 Independent retail 1
  • 214 White-collar workers in the textile industry 1
  • 220 White-collar workers in the food industry 1
  • 222 White-collar workers in paper and cardboard processing 1
  • 302 Hotels and catering 1
  • 323 Building management, estate agents and domestic staff 1
  • 330 Health institutions and services 1

Source: the annual accounts at the National Bank. One filing can name more than one committee.

Foreign control in NACE division 21

309 registered companies

Subsidies in this sector

per register · legal entities with an enterprise number
  • Flemish subsidies €65.0m awarded 71 recipients · 2022 to 2025 · largest: Onderzoeksproject
  • Federal transfers 1.2m amount as published 2 recipients · 2023 to 2025 · largest: Subsidies voor de verbetering van telecommunicatieconnectiviteit
  • EU budget €15.6m attributed share 10 recipients · 2021 to 2025 · largest: Horizon Europe
  • EU research €38.2m EU contribution 15 recipients · 2008 to 2026 · largest: Horizon 2020

Explore every recipient in this sector

Insights on Pharmaceuticals

Balance sheet and result. 40.1% of the annual accounts close with a loss, against 26.7% in Belgium. 18.3% of the annual accounts show negative equity, against 12.4% in Belgium. The median net result of €23,776 is above Belgium's €16,516.

Bankruptcies. The median bankruptcy probability of 0.3% is above Belgium's 0.2%. By size, the median bankruptcy probability is 0.4% at under 10 FTE and 0.4% at 10 to 49 FTE.

Inflow and structure. 4.5% of the companies are sole traders, against 41.6% in Belgium. Wallonia holds 38.6% of the seats, against 22.7% in Belgium. In 12 months, 2.9 of 100 companies started, against 8.9 in Belgium. That is fewer than in 88% of the 86 other NACE divisions.

Staff and filing. The median staff cost per FTE of €94,210 is above Belgium's €61,417. 32.2% of the financial year 2024 accounts were filed late, against 38.4% in Belgium. The 5 largest employers hold 19,918 of the 30,792 FTE: 64.7%.

Direction. Median solvency rose from 34.8% in financial year 2020 to 44.9% in financial year 2025. The median net result rose from €20,327 in financial year 2020 to €23,776 in financial year 2025.

The comparison with Belgium as a whole and with the other divisions is as of 07-11-2026 05:30.

Method and sources

Every company registered today counts under its main activities in the KBO. Establishment units do not count. Staff counts once, under the employer's first main activity, from its latest accounts and only where it fits the staff costs. The count follows the NACE 2025 classification, the version in which code 21 exists.

The bankruptcies over five years count only companies still registered today, because the activity of a company that left the register is not kept. So they are fewer than the bankruptcies of those years, and the figure is not a probability for the future. Over twelve months the count is nearly complete, because a bankrupt company stays registered while its bankruptcy runs. A company with more than one main activity counts in each of those sectors.

The comparison with Belgium as a whole and with the other NACE divisions rests on an overview of every division, counted again each night. Each division is counted in the version of the NACE classification in which it exists. A standing such as "more than in 80%" compares with the other divisions that have the figure. A division's bankruptcy probability is the median over its companies with a score. Belgium here counts the 1,276,547 companies with a main activity, because only those belong to a division. The other 699,272 registrations publish no activity.

Each median is the value of the middle company, computed over the annual accounts of financial year 2025, and is shown only from 30 accounts. A share (loss-making, negative equity) counts that year's accounts with that trait. Accounts are late when they are filed after the statutory deadline. Missing or 90 days late counts the companies with accounts missing today, or whose latest were filed more than 90 days after the deadline. The dossier follows the same rule.